Based on the 1982 novel Ciudades Desiertas (Deserted Cities) by Mexican writer José Agustín, You’re Killing Me Susana tells the story of Eligio (the irrepressible Gael García Bernal), a man who wakes up one day to find out that his wife, Susana (Verónica Echegui), has left him without warning.
What follows is Eligio’s earnest quest to win his wife back by following her into the United States where he must navigate cross-cultural differences and come to terms with his own chauvinistic masculinity. While Eligio is certainly presented as a caricature of macho insufferability, his wife Susana is not much better – both are equally self-obsessed to the point of interpersonal destruction.
You Are Killing Me Susana is a test of marital tensions and an exposé on the capacity for people to hurt the ones they love the most.